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Production of Mesenchymal Stem Cells through Stem Cell Reprogramming

18 Apr 2019

Abstract excerpt

Mesenchymal stem cells (MSCs) possess a broad spectrum of therapeutic applications and have been used in clinical trials. MSCs are mainly retrieved from adult or fetal tissues. However, there are many obstacles with the use of tissue-derived MSCs, such as shortages of tissue sources, difficult and invasive retrieval methods, cell population heterogeneity, low purity, cell senescence, and loss of pluripotency and...

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PMID: 31003536
DOI: 10.3390/ijms20081922

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