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Article

Association between changes in gene signatures expression and disease activity among patients with systemic lupus erythematosus

9 Jan 2019

Abstract excerpt

BACKGROUND: We assessed the stability of BAFF, interferon, plasma cell and LDG neutrophil gene expression signatures over time, and whether changes in expression coincided with changes in SLE disease activity. METHODS: Two hundred forty-three patients with SLE were evaluated for disease activity, serological parameters and peripheral blood gene signatures in clinic visits (2 or more per patient) that occurred...

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PMID: 30626389
DOI: 10.1186/s12920-018-0468-1

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