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In vitro and in vivo mouse follicle development in ovaries and reaggregated ovaries

2 Jan 2019

Abstract excerpt

Follicle development requires complex and coordinated interactions between both the oocyte and its associated somatic cells. In ovarian dysfunction, follicle development may be abnormal due to defective somatic cell function; for example, premature ovarian insufficiency or malignancies. Replacing defective somatic cells, using the reaggregated ovary (RO) technique, may 'rescue' follicle development. ROs...

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PMID: 30601757
DOI: 10.1530/rep-18-0115

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