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Article

Dysregulation of follicle development in a mouse model of premature ovarian insufficiency.

Reproduction (Cambridge, England) - 1 Nov 2016

Grasa P, Sheikh S, Krzys N, Millar K, Janjua S, Nawaggi P, Williams S A

Abstract excerpt

Premature ovarian insufficiency (POI) occurs in 1% of reproductive-age women. The ovarian manifestation ranges from the presence of a variable population of follicles (follicular) to the absence of follicles (afollicular), and in the majority of cases the cause is unknown. A transgenic mouse model of follicular POI, the Double Mutant (DM), arises from oocyte-specific deletion of Mgat1 and C1galt1 required for the...

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Source

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Identifiers

PMID: 27581083
DOI: 10.1530/REP-16-0091
PMCID: PMC5111581

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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