Article

Germline Stem Cells and Follicular Renewal in the Postnatal Mammalian Ovary

2004-06-14

Abstract excerpt

Up to now, the accepted wisdom was that, unlike males who retain germline stem cells (GSCs) through their adult lives, oocyte production in females of most mammalian species ceases before birth. Females therefore are born with a fixed pool of GSCs, or oocytes, all of them arrested in meiosis. The ovarian follicles are oocytes enclosed by somatic cells. The oocyte reserve in human females is exhausted at approximat...

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Literature Corpus work: e6e749a5-cf85-5941-917b-21c8a37f52dc
DOI: 10.1097/00006254-200407000-00017

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