Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction of ERα and NRF2 Impacts Survival in Ovarian Cancer Patients

29 Dec 2018

Abstract excerpt

Nuclear factor erythroid 2-related factor 2 (NRF2) regulates cytoprotective antioxidant processes. In this study, the prognostic potential of NRF2 and its interactions with the estrogen receptor α (ERα) in ovarian cancer cells was investigated. NRF2 and ERα protein expression in ovarian cancer tissue was analyzed as well as mRNA expression of NRF2 (NFE2L2) and ERα (ESR1) in four ovarian cancer and one benign cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endometriosis Research and Treatment
Share to Genomics, phytochemicals, and oxidative stress
Share to Ovarian cancer diagnosis and treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30597961
DOI: 10.3390/ijms20010112

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction of ERα and NRF2 Impacts Survival in Ovarian Cancer PatientsPMID 30597961Read ↗

Nrf2, the master redox switch: the Achilles' heel of ovarian cancer?Semantic proximity Read ↗

Immune phenotype in high- versus low-NRF2 high grade serous ovarian cancer and the impact on prognosisSemantic proximity Read ↗

Nuclear Factor Erythroid 2-Related Factor 2 in Regulating Cancer Metabolism.Semantic proximity Read ↗

Role of nuclear factor erythroid 2-related factor 2 (Nrf2) in female and male fertilitySemantic proximity Read ↗

Oxidative Stress-Related KEAP1 and NRF2 Genes Contributed to the Risk of Epithelial Ovarian Cancer.Semantic proximity Read ↗

Genetic polymorphisms and protein expression of NRF2 and Sulfiredoxin predict survival outcomes in breast cancer.Semantic proximity Read ↗

ABCF2 , an Nrf2 target gene, contributes to cisplatin resistance in ovarian cancer cellsSemantic proximity Read ↗

High NRF2 expression controls endoplasmic reticulum stress induced apoptosis in multiple myelomaSemantic proximity Read ↗

Oncogenic Activation of Nrf2, Though as a Master Antioxidant Transcription Factor, Liberated by Specific Knockout of the Full-Length Nrf1α that Acts as a Dominant Tumor RepressorSemantic proximity Read ↗

Synergism and antagonism of two distinct, but confused, Nrf1 factors in integral regulation of the nuclear-to-mitochondrial respiratory and antioxidant transcription networksSemantic proximity Read ↗

Nuclear Respiratory Factor 1 Acting as an Oncoprotein Drives Estrogen-Induced Breast CarcinogenesisSemantic proximity Read ↗

NRF1 Predominantly Causes EZH2 Overexpression in Cancer CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.