Article

Immune phenotype in high- versus low-NRF2 high grade serous ovarian cancer and the impact on prognosis

2025-07-22

Abstract excerpt

<title>Abstract</title> <p> <italic>NRF2</italic> modulates tumor immune microenvironment (IMM) in several cancers. NRF2 is activated in about 50% of high grade serous ovarian cancer (HGSOC), the most aggressive type of ovarian cancer. This study aimed to stratify HGSOC patients’ samples by NRF2 levels and identify its impact on immune phenotype and prognosis. We analyzed data from n = 7 scRNA-seq, n = 365 RNA-...

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Literature Corpus work: 9af37deb-b986-5949-a715-865860c9bb6b
DOI: 10.21203/rs.3.rs-6925656/v1

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