Article
Multidrug resistance phenotype: Relation between phenotype induction and its characteristics in erythroleukemia cells.
Cell biology international - 1 Feb 2019
Soares Fernanda Saldanha, Lettnin Aline Portantiolo, Wagner Eduardo Felipe, Mattozo Francielly Hafele, Carrett-Dias Michele, Rumjanek Vivian Mary Barral Dodd, Filgueira Daza Moraes Vaz Batista, de Souza Votto Ana Paula
Abstract excerpt
Chemotherapy may be followed by multiple drug resistance (MDR). This is an obstacle in the treatment of cancer. It is therefore essential to understand the mechanisms underlying tumor resistance, especially those involved in the cell target/MDR relationship. To investigate this, the effects of exposing cells to UVB (to target DNA), UVA, and H2 O2 (to target the cell membrane) were observed in K562 (non MDR) and...
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