Article
Toxicity mechanisms of onion (Allium cepa) extracts and compounds in multidrug resistant erythroleukemic cell line.
Biological research - 1 Jan 2010
Votto Ana P S, Domingues Beatriz S, de Souza Michele M, da Silva Júnior Flavio M R, Caldas Sergiane S, Filgueira Daza M V B, Clementin Rosilene M, Primel Ednei G, Vallochi Adriana L, Furlong Eliana B, Trindade Gilma S
Abstract excerpt
Onion (Allium cepa) is being studied as a potential anticancer agent, but little is known regarding its effect in multidrug resistance (MDR) cells. In this work, the cytotoxicity of crude onion extract (OE) and fractioned extract (aqueous, methanolic and ethyl acetate), as well as some onion compounds (quercetin and propyl disulfide) were evaluated in Lucena MDR human erythroleukemic and its K562 parental cell...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.