New Insights Into the Role of Qa-2 and HLA-G Non-classical MHC-I Complexes in Malignancy

Abstract excerpt

It is well established that the immune system can identify and destroy neoplastic transformed cells in a process known as immunosurveillance. Most studies have focused on the classical major histocompatibility complex (MHC) class Ia molecules, which are known to play an important role on the presentation of tumor antigens to the immune system in order to activate a response against tumor cells. However, a larger...

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