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Article

Clinical Phenotype and Genotype Associations With Improvement in Left Ventricular Function in Dilated Cardiomyopathy

1 Nov 2018

Abstract excerpt

Background: Improvement of left ventricular function (also called left ventricular reverse remodeling [LVRR]) is an important treatment goal in patients with dilated cardiomyopathy (DCM) and hypokinetic non-DCM (HNDC) and is prognostically favorable. We tested whether genetic DCM mutations impact LVRR independent from clinical parameters. Methods and Results: Patients with DCM and hypokinetic non-DCM (n=346; mean...

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PMID: 30571196
DOI: 10.1161/circheartfailure.118.005220

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