Genetic basis of cardiomyopathy and the genotypes involved in prognosis and left ventricular reverse remodeling.

doi:10.1038/s41598-018-20114-9

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Article

Genetic basis of cardiomyopathy and the genotypes involved in prognosis and left ventricular reverse remodeling.

Scientific reports - 31 Jan 2018

Tobita Takashige, Nomura Seitaro, Fujita Takanori, Morita Hiroyuki, Asano Yoshihiro, Onoue Kenji, Ito Masamichi, Imai Yasushi, Suzuki Atsushi, Ko Toshiyuki, Satoh Masahiro, Fujita Kanna, Naito Atsuhiko T, Furutani Yoshiyuki, Toko Haruhiro, Harada Mutsuo, Amiya Eisuke, Hatano Masaru, Takimoto Eiki, Shiga Tsuyoshi, Nakanishi Toshio, Sakata Yasushi, Ono Minoru, Saito Yoshihiko, Takashima Seiji, Hagiwara Nobuhisa, Aburatani Hiroyuki, Komuro Issei

Abstract excerpt

Dilated cardiomyopathy (DCM) and hypertrophic cardiomyopathy (HCM) are genetically and phenotypically heterogeneous. Cardiac function is improved after treatment in some cardiomyopathy patients, but little is known about genetic predictors of long-term outcomes and myocardial recovery following medical treatment. To elucidate the genetic basis of cardiomyopathy in Japan and the genotypes involved in prognosis and...

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Identifiers

PMID: 29386531
DOI: 10.1038/s41598-018-20114-9
PMCID: PMC5792481

Genes

LMNA
TTN
MYBPC3
MYH7

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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