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Article

Genotype is associated with left ventricular reverse remodelling and early events in recent-onset dilated cardiomyopathy.

ESC heart failure - 1 Dec 2024

Kubanek Milos, Binova Jana, Piherova Lenka, Krebsova Alice, Kotrc Martin, Hartmannova Hana, Hodanova Katerina, Musalkova Dita, Stranecky Viktor, Palecek Tomas, Chaloupka Anna, Grochova Ilga, Krejci Jan, Petrkova Jana, Melenovsky Vojtech, Kmoch Stanislav, Kautzner Josef

Abstract excerpt

AIMS: Recent-onset dilated cardiomyopathy (RODCM) is characterized by heterogeneous aetiology and diverse clinical outcomes, with scarce data on genotype-phenotype correlates. Our aim was to correlate individual RODCM genotypes with left ventricular reverse remodelling (LVRR) and clinical outcomes. METHODS AND RESULTS: In this prospective study, a total of 386 Czech RODCM patients with symptom duration ≤6 months...

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Identifiers

PMID: 39129193
DOI: 10.1002/ehf2.15009
PMCID: PMC11631235

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