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Influence of Cell Morphology on Mesenchymal Stem Cell Transfection

20 Dec 2018

Abstract excerpt

Gene transfection has broad applications in bioengineering and biomedical fields. Although many gene carrier materials and transfection methods have been developed, it remains unclear how cell morphology including cell spreading and elongation affects gene transfection. In this study, human bone marrow-derived mesenchymal stem cells (hMSCs) were cultured on micropatterns and transfected with cationic pAcGFP1-N1...

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PMID: 30571082
DOI: 10.1021/acsami.8b20490

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