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E7-Modified Substrates to Promote Adhesion and Maintain Stemness of Mesenchymal Stem Cells.

Macromolecular bioscience - 1 Apr 2021

Ge Qunzi, Wang Xuemei, Luo Yu, Zheng Xiaowen, Ma Lie

Abstract excerpt

Mesenchymal stem cells (MSCs) have drawn great attention in clinical applications due to the self-renewal ability, multi-differentiation potential, and low immunogenicity. However, there are challenges in the ex vivo expansion of MSCs, including low efficiency, stemness loss, and safety. Therefore, it is crucial to construct a substrate that can show an alterable affinity to MSCs, and induce efficient cell...

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PMID: 33480478
DOI: 10.1002/mabi.202000384

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