Article
Analysis of Gene Expression from Systemic Lupus Erythematosus Synovium Reveals a Profile of Activated Immune Cells and Inflammatory Pathways
2020-06-20
Abstract excerpt
<h4>ABSTRACT</h4> Arthritis is a common manifestation of systemic lupus erythematosus (SLE) yet understanding of the underlying pathogenic mechanisms remains incomplete. We, therefore, interrogated gene expression profiles of SLE synovium to gain insight into the nature of lupus arthritis (LA), using osteoarthritis (OA) and rheumatoid arthritis (RA) as comparators. Knee synovia from SLE, OA, and RA patients were...
Topics
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- Atherosclerosis and Cardiovascular Diseases
- Cytokine Signaling Pathways and Interactions
- Inflammatory mediators and NSAID effects
- Lymphoma Diagnosis and Treatment
- Osteoarthritis Treatment and Mechanisms
- Protein Tyrosine Phosphatases
- Rheumatoid Arthritis Research and Therapies
- Systemic Lupus Erythematosus Research
Identifiers and source
- Literature Corpus work
- 703bf4c3-20fe-5541-9404-3605de93a6af
- DOI
- 10.1101/2020.06.19.123307
