Article
Lutzomyia longipalpis Saliva Induces Heme Oxygenase-1 Expression at Bite Sites
28 Nov 2018
Abstract excerpt
Sand flies bite mammalian hosts to obtain a blood meal, driving changes in the host inflammatory response that support the establishment of Leishmania infection. This effect is partially attributed to components of sand fly saliva, which are able to recruit and activate leukocytes. Our group has shown that heme oxygenase-1 (HO-1) favors Leishmania survival in infected cells by reducing inflammatory responses....
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