Article
Canine leishmaniasis: Genome-wide analysis and antibody response to Lutzomyia longipalpis saliva.
PloS one - 1 Jan 2018
Batista Luís F S, Utsunomiya Yuri T, Silva Thaís B F, Carneiro Mariana M, Paiva Joyr S F, Silva Rafaela B, Tomokane Thaíse Y, Rossi Claudio N, Pacheco Acácio D, Torrecilha Rafaela B P, Silveira Fernando T, Marcondes Mary, Nunes Cáris M, Laurenti Márcia D
Abstract excerpt
The anti-inflammatory properties of sand fly saliva favor the establishment of the Leishmania infantum infection. In contrast, an antibody response against Lutzomyia longipalpis saliva is often associated with a protective cell-mediated response against canine visceral leishmaniasis. Genetic studies may demonstrate to what extent the ability to secrete anti-saliva antibodies depends on genetic or environmental...
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