Molecular Diversity between Salivary Proteins from New World and Old World Sand Flies with Emphasis on Bichromomyia olmeca, the Sand Fly Vector of Leishmania mexicana in Mesoamerica.

doi:10.1371/journal.pntd.0004771

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Molecular Diversity between Salivary Proteins from New World and Old World Sand Flies with Emphasis on Bichromomyia olmeca, the Sand Fly Vector of Leishmania mexicana in Mesoamerica.

PLoS neglected tropical diseases - 1 Jul 2016

Abdeladhim Maha, V Coutinho-Abreu Iliano, Townsend Shannon, Pasos-Pinto Silvia, Sanchez Laura, Rasouli Manoochehr, B Guimaraes-Costa Anderson, Aslan Hamide, Francischetti Ivo M B, Oliveira Fabiano, Becker Ingeborg, Kamhawi Shaden, Ribeiro Jose M C, Jochim Ryan C, Valenzuela Jesus G

Abstract excerpt

BACKGROUND: Sand fly saliva has been shown to have proteins with potent biological activities, salivary proteins that can be used as biomarkers of vector exposure, and salivary proteins that are candidate vaccines against different forms of leishmaniasis. Sand fly salivary gland transcriptomic approach has contributed significantly to the identification and characterization of many of these salivary proteins from...

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PMID: 27409591
DOI: 10.1371/journal.pntd.0004771
PMCID: PMC4943706

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