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Article

Modified VEGF-A mRNA induces sustained multifaceted microvascular response and accelerates diabetic wound healing

26 Nov 2018

Abstract excerpt

Capable of mediating efficient transfection and protein production without eliciting innate immune responses, chemically modified mRNA holds great potential to produce paracrine factors at a physiologically beneficial level, in a spatiotemporally controlled manner, and with low toxicity. Although highly promising in cardiovascular medicine and wound healing, effects of this emerging therapeutic on the...

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PMID: 30504800
DOI: 10.1038/s41598-018-35570-6

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