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VDR polymorphism, gene expression and vitamin D levels in leprosy patients from North Indian population

27 Nov 2018

Abstract excerpt

BACKGROUND: Leprosy is a chronic infectious disease caused by Mycobacterium leprae and mainly affects skin, peripheral nerves. Vitamin D receptor (VDR) gene polymorphism has been found to be associated with leprosy. Vitamin D has been shown to control several host immunomodulating properties through VDR gene. Vitamin D deficiency was also found to be linked to an increased risk for several infections and...

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PMID: 30481178
DOI: 10.1371/journal.pntd.0006823

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