Article
Association of Taq I, Fok I and Apa I polymorphisms in Vitamin D Receptor (VDR) gene with leprosy.
Human immunology - 1 Jun 2015
Neela Venkata Sanjeev Kumar, Suryadevara Naveen Chandra, Shinde Vidya Gouri, Pydi Satya Sudheer, Jain Suman, Jonnalagada Subbanna, Singh Surya Satyanarayana, Valluri Vijaya Lakshmi, Anandaraj M P J S
Abstract excerpt
BACKGROUND: Vitamin D Receptor (VDR) is a transacting transcription factor which mediates immunomodulatory function and plays a key role in innate and adaptive immune responses through its ligand and polymorphisms in VDR gene may affect its regulatory function. OBJECTIVE: To investigate the association of three VDR gene polymorphisms (TaqI rs731236, FokI rs2228570 and ApaI rs7975232) with leprosy. METHODS: The...
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