Comparison of serum vitamin D level and vitamin D receptor gene FokI polymorphism in leprosy patients with and without trophic ulcers: A case-control study.

doi:10.1371/journal.pntd.0014205

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Article

Comparison of serum vitamin D level and vitamin D receptor gene FokI polymorphism in leprosy patients with and without trophic ulcers: A case-control study.

PLoS neglected tropical diseases - 1 Apr 2026

Halim Paulus Anthony, Sirait Sondang P, Miranda Eliza, Ariani Yulia, Indriatmi Wresti, Thio Hok Bing

Abstract excerpt

BACKGROUND: Alterations in the vitamin D axis have been implicated in chronic wounds, but their role in leprosy-related trophic ulcers (TU) is unclear. This study compared serum vitamin D levels and VDR FokI (rs2228570) polymorphism between leprosy patients with and without TU, assessed their association with ulcer presence, and examined the correlation between vitamin D levels and ulcer severity. METHODS: This...

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PMID: 41961906
DOI: 10.1371/journal.pntd.0014205
PMCID: PMC13086432

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