Article
Association of the polymorphism of the vitamin D receptor gene (VDR) with the risk of leprosy in the Brazilian Amazon.
Bioscience reports - 30 Jul 2021
Paz Jasna Letícia Pinto, Silvestre Maria do Perpétuo Socorro Corrêa Amador, Moura Letícia Siqueira, Furlaneto Ismari Perini, Rodrigues Yan Corrêa, Lima Karla Valéria Batista, Lima Luana Nepomuceno Gondim Costa
Abstract excerpt
The transmission and evolution of leprosy depends on several aspects, including immunological and genetic factors of the host, as well as genetic factors of Mycobacterium leprae. The present study evaluated the association of single nucleotide polymorphisms (SNPs) on the FokI (rs2228570), TaqI (rs731236), ApaI (rs7975232) regions of the vitamin D receptor (VDR) gene with leprosy. A total of 405 individuals were...
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