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Cellular Phenotype Plasticity in Cancer Dormancy and Metastasis

4 Nov 2018

Abstract excerpt

Cancer dormancy is a period of cancer progression in which residual tumor cells exist, but clinically remain asymptomatic for a long time, as well as resistant to conventional chemo- and radiotherapies. Cellular phenotype plasticity represents that cellular phenotype could convert between epithelial cells and cells with mesenchymal traits. Recently, this process has been shown to closely associate with tumor cell...

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PMID: 30456206
DOI: 10.3389/fonc.2018.00505

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