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Article

Maternal nutritional status, C<sub>1</sub>metabolism and offspring DNA methylation: a review of current evidence in human subjects

29 Nov 2011

Abstract excerpt

Evidence is growing for the long-term effects of environmental factors during early-life on later disease susceptibility. It is believed that epigenetic mechanisms (changes in gene function not mediated by DNA sequence alteration), particularly DNA methylation, play a role in these processes. This paper reviews the current state of knowledge of the involvement of C1 metabolism and methyl donors and cofactors in...

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PMID: 22124338
DOI: 10.1017/s0029665111003338

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