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New resistance mechanisms to azole drugs inAspergillus fumigatusand emergence of antifungal drugs-resistantA. fumigatusatypical strains

1 Jan 2006

Abstract excerpt

Azole drug resistance in Aspergillus fumigatus is an uncommon but well-known phenomenon. The analysis of resistance mechanisms at molecular level has identified the bases for A. fumigatus azole resistance. To date, the most prevalent mechanism of azole resistance appears to be the modification of Cyp51, specifically mutations in cyp51A gene. These mutations have been associated with three different antifungal...

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PMID: 30408931
DOI: 10.1080/13693780600902243

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