Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tissue-enhanced plasma proteomic analysis for disease stratification in amyotrophic lateral sclerosis

7 Nov 2018

Abstract excerpt

BACKGROUND: It is unclear to what extent pre-clinical studies in genetically homogeneous animal models of amyotrophic lateral sclerosis (ALS), an invariably fatal neurodegenerative disorder, can be informative of human pathology. The disease modifying effects in animal models of most therapeutic compounds have not been reproduced in patients. To advance therapeutics in ALS, we need easily accessible disease...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Amyotrophic Lateral Sclerosis Research
Share to Genetic Neurodegenerative Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30404656
DOI: 10.1186/s13024-018-0292-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tissue-enhanced plasma proteomic analysis for disease stratification in amyotrophic lateral sclerosisPMID 30404656Read ↗

Combined Tissue-Fluid Proteomics to Unravel Phenotypic Variability in Amyotrophic Lateral SclerosisSemantic proximity Read ↗

Redefining ALS: Large-scale proteomic profiling reveals a prolonged pre-diagnostic phase with immune, muscular, metabolic, and brain involvementSemantic proximity Read ↗

Proteome analysis reveals candidate markers of disease progression in amyotrophic lateral sclerosis (ALS)Semantic proximity Read ↗

Redefining ALS: Large-scale proteomic profiling reveals a prolonged pre-diagnostic phase with immune, muscular, metabolic, and brain involvementSemantic proximity Read ↗

Plasma profiling reveals three proteins associated to amyotrophic lateral sclerosisSemantic proximity Read ↗

Analysis of Circulating Protein Aggregates Reveals Pathological Hallmarks of Amyotrophic Lateral SclerosisSemantic proximity Read ↗

Muscle proteins in plasma associate to distinguished phenotypes in amyotrophic lateral sclerosisSemantic proximity Read ↗

Analysis of circulating protein aggregates reveals pathological hallmarks of amyotrophic lateral sclerosisSemantic proximity Read ↗

A plasma proteomics-based candidate biomarker panel predictive of amyotrophic lateral sclerosisSemantic proximity Read ↗

Proteomic studies in the discovery of cerebrospinal fluid biomarkers for amyotrophic lateral sclerosisSemantic proximity Read ↗

Muscle spatial lipidomics identifies early ALS-associated lipid remodeling in presymptomatic SOD1G93A miceSemantic proximity Read ↗

Skeletal muscle biomarkers of amyotrophic lateral sclerosis: a large-scale, multi-cohort proteomic studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.