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A Two-Step Approach for the Design and Generation of Nanobodies

2 Nov 2018

Abstract excerpt

Nanobodies, the smallest possible antibody format, have become of considerable interest for biotechnological and immunotherapeutic applications. They show excellent robustness, are non-immunogenic in humans, and can easily be engineered and produced in prokaryotic hosts. Traditionally, nanobodies are selected from camelid immune libraries involving the maintenance and treatment of animals. Recent advances have...

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PMID: 30400198
DOI: 10.3390/ijms19113444

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