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Genome assembly and gene expression in the American black bear provides new insights into the renal response to hibernation

4 Oct 2018

Abstract excerpt

The prevalence of chronic kidney disease (CKD) is rising worldwide and 10-15% of the global population currently suffers from CKD and its complications. Given the increasing prevalence of CKD there is an urgent need to find novel treatment options. The American black bear (Ursus americanus) copes with months of lowered kidney function and metabolism during hibernation without the devastating effects on metabolism...

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PMID: 30395234
DOI: 10.1093/dnares/dsy036

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