Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Serum plays an important role in reprogramming the seasonal transcriptional profile of brown bear adipocytes

21 Sept 2022

Abstract excerpt

Understanding how metabolic reprogramming happens in cells will aid the progress in the treatment of a variety of metabolic disorders. Brown bears undergo seasonal shifts in insulin sensitivity, including reversible insulin resistance in hibernation. We performed RNA-sequencing on brown bear adipocytes and proteomics on serum to identify changes possibly responsible for reversible insulin resistance. We observed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Adipose Tissue and Metabolism
Share to Exercise and Physiological Responses

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36317158
DOI: 10.1016/j.isci.2022.105084

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Serum plays an important role in reprogramming the seasonal transcriptional profile of brown bear adipocytesPMID 36317158Read ↗

Hibernation induces widespread transcriptional remodeling in metabolic tissues of the grizzly bearSemantic proximity Read ↗

Long-read isoform sequencing reveals tissue-specific isoform expression between active and hibernating brown bears ( <i>Ursus arctos</i> )Semantic proximity Read ↗

Brown Bears activates a Satiety Hormone Cholecystokinin (CCK) pathway in adipose tissue during hibernationSemantic proximity Read ↗

Deep Sequencing the Transcriptome Reveals Seasonal Adaptive Mechanisms in a Hibernating MammalSemantic proximity Read ↗

Widespread seasonal gene expression reveals annual differences in human immunity and physiologySemantic proximity Read ↗

Temporal dynamics of the multi-omic response to endurance exercise training across tissuesSemantic proximity Read ↗

Genes Underlying Adaptive Physiological Shifts Among Hibernating MammalsSemantic proximity Read ↗

Characterization of transcriptomic profiles underlying gross morphological changes observed in semelparous pink salmon ( <i>Oncorhynchus gorbuscha</i> )Semantic proximity Read ↗

Multidimensional Single-Nuclei RNA-Seq Reconstruction of Adipose Tissue Reveals Adipocyte Plasticity Underlying Thermogenic ResponseSemantic proximity Read ↗

Exercise modulation of the alternative splicing landscape in human tissuesSemantic proximity Read ↗

Genome assembly and gene expression in the American black bear provides new insights into the renal response to hibernationSemantic proximity Read ↗

Genome assembly and gene expression in the American black bear provides new insights into the renal response to hibernationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.