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Evaluation of a recombination-resistant coronavirus as a broadly applicable, rapidly implementable vaccine platform

23 Oct 2018

Abstract excerpt

Emerging and re-emerging zoonotic viral diseases are major threats to global health, economic stability, and national security. Vaccines are key for reducing coronaviral disease burden; however, the utility of live-attenuated vaccines is limited by risks of reversion or repair. Because of their history of emergence events due to their prevalence in zoonotic pools, designing live-attenuated coronavirus vaccines...

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PMID: 30393776
DOI: 10.1038/s42003-018-0175-7

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