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Article

A recombination-resistant genome for live attenuated and stable PEDV vaccines by engineering the transcriptional regulatory sequences.

Journal of virology - 21 Dec 2023

Niu Xiaoyu, Liu Mingde, Yang Shaomin, Xu Jiayu, Hou Yixuan J, Liu Dongxiao, Tang Qiyi, Zhu Hua, Wang Qiuhong

Abstract excerpt

IMPORTANCE: Coronaviruses are important pathogens of humans and animals, and vaccine developments against them are imperative. Due to the ability to induce broad and prolonged protective immunity and the convenient administration routes, live attenuated vaccines (LAVs) are promising arms for controlling the deadly coronavirus infections. However, potential recombination events between vaccine and field strains...

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Share to Coronavirus Infections
Share to Porcine epidemic diarrhea virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Recombination, Genetic

Share to Swine Diseases

Share to Vaccines, Attenuated

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Source

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Identifiers

PMID: 37971221
DOI: 10.1128/jvi.01193-23
PMCID: PMC10734454

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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