Article
The B7-H3/CD3 immune phenotype identifies prognostic subgroups in neuroblastoma.
Frontiers in immunology - 1 Jan 2026
Rasic Petar, Samardzija Gordana, Djuricic Slavisa M, Mitrovic Nemanja, Bogosavljevic Ana, Milicevic Andjela, Soldatovic Ivan, Stefanovic Olivera, Krstovski Nada, Kuzmanovic Milos, Aleksic Dragana, Redzic Danka, Rodic Predrag, Lazic Jelena, Milosevic Goran, Svorcan Jovana, Radeta Ratko, Milickovic Maja, Dundjerovic Dusko
Abstract excerpt
Introduction: B7-H3 is an immune checkpoint molecule implicated in tumor immune evasion and adverse prognosis in multiple malignancies. This study aimed to characterize the relationships between tumor-cell B7-H3 expression, immune-cell infiltration, clinicopathological features, and survival in malignant neuroblastic tumors, and to define an immune phenotype with potential translational relevance. Methods: We...
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