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Article

Preferred end coordinates and somatic variants as signatures of circulating tumor DNA associated with hepatocellular carcinoma

29 Oct 2018

Abstract excerpt

Circulating tumor-derived cell-free DNA (ctDNA) analysis offers an attractive noninvasive means for detection and monitoring of cancers. Evidence for the presence of cancer is dependent on the ability to detect features in the peripheral circulation that are deemed as cancer-associated. We explored approaches to improve the chance of detecting the presence of cancer based on sequence information present on ctDNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30373822
DOI: 10.1073/pnas.1814616115

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