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Article

Novel targeting approaches and signaling pathways of colorectal cancer: An insight

19 Oct 2018

Abstract excerpt

Colorectal cancer (CRC) is the third most common cancer of mortality in the world. Chemotherapy based treatment leads to innumerable side effects as it delivers the anticancer drug to both normal cells besides cancer cells. Sonic Hedgehog (SHH), Wnt wingless-type mouse mammary tumor virus/β-catenin, transforming growth factor-β/SMAD, epidermal growth factor receptor and Notch are the main signaling pathways...

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PMID: 30357011
DOI: 10.3748/wjg.v24.i39.4428

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