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Article

General Aspects of Colorectal Cancer

14 Nov 2012

Abstract excerpt

Colorectal cancer (CRC) is one of the main causes of death. Cancer is initiated by several DNA damages, affecting proto-oncogenes, tumour suppressor genes, and DNA repairing genes. The molecular origins of CRC are chromosome instability (CIN), microsatellite instability (MSI), and CpG island methylator phenotype (CIMP). A brief description of types of CRC cancer is presented, including sporadic CRC, hereditary...

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PMID: 23209942
DOI: 10.5402/2012/139268

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