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Diagnostic application of kidney allograft-derived absolute cell-free DNA levels during transplant dysfunction

12 Oct 2018

Abstract excerpt

Graft-derived cell-free DNA (donor-derived cell-free DNA) is an emerging marker of kidney allograft injury. Studies examining the clinical validity of this biomarker have previously used the graft fraction, or proportion of total cell-free DNA that is graft-derived. The present study evaluated the diagnostic validity of absolute measurements of graft-derived cell-free DNA, as well as calculated graft fraction,...

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PMID: 30312536
DOI: 10.1111/ajt.15142

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