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Difference of molecular alterations in HER2-positive and HER2-negative gastric cancers by whole-genome sequencing analysis

1 Sept 2018

Abstract excerpt

Objective: The aim of this study was to compare the molecular profiling, including somatic mutation and somatic copy number variation (SCNV), between human epidermal growth factor receptor 2 (HER2)-positive (HER2+) and HER2-negative (HER2–) gastric cancer patients. Patients and methods: Tumor samples were collected from 15 gastric cancer patients, including 10 HER2+ samples and five HER2– samples, which were...

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PMID: 30310315
DOI: 10.2147/cmar.s172710

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