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Article

Molecular characteristics of gastric cancer with ERBB2 amplification

25 Jul 2023

Abstract excerpt

Gastric cancer is a prevalent malignancy with a high degree of heterogeneity, which has led to a poor therapeutic response. Though there are numerous HER2-targeted medicines for HER2+ gastric cancer, many trials have not indicated an improvement in overall survival. Here 29 ERBB2 amplification ( ERBB2 -Amp) type gastric cancer samples with WES and RNA-seq data were selected for investigation, which copy-number...

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Identifiers

PMID: 37554835
DOI: 10.1016/j.heliyon.2023.e18654

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