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Klinefelter syndrome in males with germ cell tumors: A report from the Children's Oncology Group

1 Oct 2018

Abstract excerpt

BACKGROUND: Males with Klinefelter syndrome (KS) (47,XXY) may be more likely to develop germ cell tumors (GCTs), particularly mediastinal GCTs. To date, there are no reports characterizing the prevalence of KS among male GCT cases. METHODS: The authors used array genotyping data from a Children's Oncology Group epidemiology study to estimate the prevalence of KS in males with GCTs (433 males aged birth-19 years)....

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PMID: 30291793
DOI: 10.1002/cncr.31667

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