Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differences in DNA methylation profiles by histologic subtype of paediatric germ cell tumours: a report from the Children’s Oncology Group

1 Oct 2018

Abstract excerpt

BACKGROUND: Abnormal DNA methylation may be important in germ cell tumour (GCT) aetiology, as germ cells undergo complete epigenetic reprogramming during development. GCTs show differences in global and promoter methylation patterns by histologic subtype. We conducted an epigenome-wide study to identify methylation differences by GCT histology. METHODS: Using the Illumina HumanMethylation450K array we measured...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Glioma Diagnosis and Treatment
Share to Testicular diseases and treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30287918
DOI: 10.1038/s41416-018-0277-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differences in DNA methylation profiles by histologic subtype of paediatric germ cell tumours: a report from the Children’s Oncology GroupPMID 30287918Read ↗

DNA methylation analysis reveals distinct methylation signatures in pediatric germ cell tumorsSemantic proximity Read ↗

Genome Wide DNA Methylation Profiles Provide Clues to the Origin and Pathogenesis of Germ Cell TumorsSemantic proximity Read ↗

Identification and validation of liquid biopsy-based methylation biomarkers: a germ cell tumor subtype-specific studySemantic proximity Read ↗

Pediatric Malignant Germ Cell Tumors Show Characteristic Transcriptome ProfilesSemantic proximity Read ↗

Methylator phenotype of malignant germ cell tumours in children identifies strong candidates for chemotherapy resistance.Semantic proximity Read ↗

Comprehensive genetic analysis of pediatric germ cell tumors identifies potential drug targets.Semantic proximity Read ↗

Transcriptome and methylome analysis of CNS germ cell tumor finds its cell-of-origin in embryogenesis and reveals shared similarities with testicular counterparts.Semantic proximity Read ↗

Pediatric primary central nervous system germ cell tumors of different prognosis groups show characteristic miRNome traits and chromosome copy number variationsSemantic proximity Read ↗

Integrated Molecular Characterization of Testicular Germ Cell TumorsSemantic proximity Read ↗

The two most common histological subtypes of malignant germ cell tumour are distinguished by global microRNA profiles, associated with differential transcription factor expressionSemantic proximity Read ↗

Cross platform analysis of methylation, miRNA and stem cell gene expression data in germ cell tumors highlights characteristic differences by tumor histology.Semantic proximity Read ↗

Integrated genomic analysis reveals aberrations in WNT signaling in germ cell tumors of childhood and adolescenceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.