Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Amino Acid Residue 217 in the Hemagglutinin Glycoprotein Is a Key Mediator of Avian Influenza H7N9 Virus Antigenicity

4 Oct 2018

Abstract excerpt

Avian influenza H7N9 viruses circulating in poultry and wild birds continue to evolve and acquire important phenotypic changes. Mutations to the virus hemagglutinin (HA) glycoprotein can modulate virus antigenicity and facilitate virus escape from natural or vaccine-induced immunity. The focus of this study was to identify evolutionary markers in the HA of H7N9 that drive escape from antibody-based immunity. To...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Disease Management and Epidemiology
Share to Immune Response and Inflammation
Share to Influenza Virus Research Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30282714
DOI: 10.1128/jvi.01627-18

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Amino Acid Residue 217 in the Hemagglutinin Glycoprotein Is a Key Mediator of Avian Influenza H7N9 Virus AntigenicityPMID 30282714Read ↗

Immune Escape Adaptive Mutations in the H7N9 Avian Influenza Hemagglutinin Protein Increase Virus Replication Fitness and Decrease Pandemic Potential.Semantic proximity Read ↗

Epitopes in the HA and NA of H5 and H7 avian influenza viruses that are important for antigenic driftSemantic proximity Read ↗

Identification of Amino Acid Substitutions Supporting Antigenic Change of Influenza A(H1N1)pdm09 VirusesSemantic proximity Read ↗

Substitutions near the receptor binding site determine major antigenic change during influenza virus evolution.Semantic proximity Read ↗

Plasticity of the Influenza Virus H5 HA Protein.Semantic proximity Read ↗

220 mutation in the hemagglutinin of avian influenza A (H7N9) virus alters antigenicity during vaccine strain development.Semantic proximity Read ↗

Antigenic Drift of the Pandemic 2009 A(H1N1) Influenza Virus in a Ferret ModelSemantic proximity Read ↗

Immune Escape Adaptive Mutations in Hemagglutinin Are Responsible for the Antigenic Drift of Eurasian Avian-Like H1N1 Swine Influenza Viruses.Semantic proximity Read ↗

Key Amino Acid Residues That Determine the Antigenic Properties of Highly Pathogenic H5 Influenza Viruses Bearing the Clade 2.3.4.4 Hemagglutinin GeneSemantic proximity Read ↗

Identification of Hemagglutinin Residues Responsible for H3N2 Antigenic Drift during the 2014-2015 Influenza Season.Semantic proximity Read ↗

Impact of a large deletion in the neuraminidase protein identified in a laninamivir-selected influenza A/Brisbane/10/2007 (H3N2) variant on viral fitness in vitro and in ferrets.Semantic proximity Read ↗

Airborne Transmission of Highly Pathogenic H7N1 Influenza Virus in FerretsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.