Article
Integrin alpha 6 regulates glioblastoma stem cells.
Cell stem cell - 7 May 2010
Lathia Justin D, Gallagher Joseph, Heddleston John M, Wang Jialiang, Eyler Christine E, Macswords Jennifer, Wu Qiulian, Vasanji Amit, McLendon Roger E, Hjelmeland Anita B, Rich Jeremy N
Abstract excerpt
Cancer stem cells (CSCs) are a subpopulation of tumor cells suggested to be critical for tumor maintenance, metastasis, and therapeutic resistance. Prospective identification and targeting of CSCs are therefore priorities for the development of novel therapeutic paradigms. Although CSC enrichment has been achieved with cell surface proteins including CD133 (Prominin-1), the roles of current CSC markers in tumor...
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