Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma

7 Dec 2016

Abstract excerpt

Abstract Non-CG methylation has been associated with stemness regulation in embryonic stem cells. By comparing differentially expressed genes affected by non-CG methylation between tumour and corresponding non-tumour tissues in oesophageal squamous cell carcinoma (OSCC), we find that Integrin α7 ( ITGA7 ) is characterized as a potential cancer stem cell (CSC) marker. Clinical data show that a high frequency of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer-related gene regulation
Share to Cell Adhesion Molecules Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27924820
DOI: 10.1038/ncomms13568

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinomaPMID 27924820Read ↗

Integrins regulate stemness in solid tumor: an emerging therapeutic target.Semantic proximity Read ↗

Advancement in Cancer Stem Cell Biology and Precision Medicine—Review Article Head and Neck Cancer Stem Cell Plasticity and the Tumor MicroenvironmentSemantic proximity Read ↗

Integrin α6 (CD49f), The Microenvironment and Cancer Stem CellsSemantic proximity Read ↗

The Cancer Stem Cell Marker CD44 Play Key Roles in Immune Suppression/Evasion, Drug Resistance, Epithelial-Mesenchymal Transition, and Metastasis in Several Human CancersSemantic proximity Read ↗

Transcription Elongation Factor A-like 7 is a Stemness-Related Prognostic Factor in Gastric CancerSemantic proximity Read ↗

Identification of a cancer stem cell-specific function for the histone deacetylases, HDAC1 and HDAC7, in breast and ovarian cancer.Semantic proximity Read ↗

Cancer Stem Cell Marker CD44 Plays Multiple Key Roles in Human Cancers: Immune Suppression/Evasion, Drug Resistance, Epithelial–Mesenchymal Transition, and MetastasisSemantic proximity Read ↗

Positive Correlations of Oct-4 and Nanog in Oral Cancer Stem-Like Cells and High-Grade Oral Squamous Cell CarcinomaSemantic proximity Read ↗

CD44v8-10 Is a Cancer-Specific Marker for Gastric Cancer Stem CellsSemantic proximity Read ↗

The Tumor-Associated Glycosyltransferase ST6Gal-I Regulates Stem Cell Transcription Factors and Confers a Cancer Stem Cell Phenotype.Semantic proximity Read ↗

Pan-cancer genomic amplifications underlie a Wnt hyperactivation phenotype associated with stem cell-like features leading to poor prognosisSemantic proximity Read ↗

Hyaluronan-CD44 interaction promotes oncogenic signaling, microRNA functions, chemoresistance, and radiation resistance in cancer stem cells leading to tumor progression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.