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The plasminogen binding protein PbsP is required for brain invasion by hypervirulent CC17 Group B streptococci

19 Sept 2018

Abstract excerpt

Streptococcus agalactiae (Group B Streptococcus or GBS) is a frequent cause of serious disease in newborns and adults. Epidemiological evidence indicates a strong association between GBS strains belonging to the hypervirulent CC17 clonal complex and the occurrence of meningitis in neonates. We investigate here the role of PbsP, a cell wall plasminogen binding protein, in colonization of the central nervous system...

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PMID: 30254272
DOI: 10.1038/s41598-018-32774-8

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