Article
Human sodium/iodide symporter-mediated radioiodine gene therapy enhances the killing activities of CTLs in a mouse tumor model.
Molecular cancer therapeutics - 1 Jan 2010
Jeon Yong Hyun, Choi Yun, Kim Chul Woo, Kim Young-Hwa, Youn Hyewon, Lee Jaetae, Chung June-Key
Abstract excerpt
We examined whether human sodium/iodide symporter (hNIS) radioiodine gene therapy can modulate the phenotype of cancer cells and enhance the killing activities of CTLs in a mouse tumor model. Various doses of I-131 (75, 300, 600, 1,200, and 2,400 microCi/5 mL) were incubated with hNIS-expressing...
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