Article
Genome-scale metabolic reconstructions of multiple Salmonella strains reveal serovar-specific metabolic traits.
Nature communications - 14 Sept 2018
Seif Yara, Kavvas Erol, Lachance Jean-Christophe, Yurkovich James T, Nuccio Sean-Paul, Fang Xin, Catoiu Edward, Raffatellu Manuela, Palsson Bernhard O, Monk Jonathan M
Abstract excerpt
Salmonella strains are traditionally classified into serovars based on their surface antigens. While increasing availability of whole-genome sequences has allowed for more detailed subtyping of strains, links between genotype, serovar, and host remain elusive. Here we reconstruct genome-scale metabolic models for 410 Salmonella strains spanning 64 serovars. Model-predicted growth capabilities in over 530...
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