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Successful transplantation of spermatogonial stem cells into the seminiferous tubules of busulfan-treated mice

23 Sept 2021

Abstract excerpt

BACKGROUND: Spermatogonial stem cells (SSCs) in the testis are crucial for transferring genetic information to the next generation. Successful transplantation of SSCs to infertile men is an advanced therapeutic application in reproductive biology research. METHODS: In this experimental research, both in vitro and in vivo characterization of undifferentiated and differentiated SSCs were performed by...

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PMID: 34556135
DOI: 10.1186/s12978-021-01242-4

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