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Article

Generation of mice by transplantation of an adult spermatogonial cell line after cryopreservation

13 Mar 2009

Abstract excerpt

OBJECTIVES: The key to fertility in adult males is production of mature spermatogenic cells. Spermatogonial stem cells (SSC) have the dual capacity of self-renewal and of differentiation into mature sperm. SSC transplantation may provide potential treatment for specific male infertilities. However, until now, there has been no evidence of offspring produced by transplantation of adult SSC line cells in humans or...

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PMID: 19317803
DOI: 10.1111/j.1365-2184.2009.00589.x

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